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Improved growth rate in Clostridium thermocellum hydrogenase mutant via perturbed sulfur metabolism

BACKGROUND: Metabolic engineering is a commonly used approach to develop organisms for an industrial function, but engineering aimed at improving one phenotype can negatively impact other phenotypes. This lack of robustness can prove problematic. Cellulolytic bacterium Clostridium thermocellum is ab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Biofuels
Hauptverfasser: Biswas, Ranjita, Wilson, Charlotte M., Giannone, Richard J., Klingeman, Dawn M., Rydzak, Thomas, Shah, Manesh B., Hettich, Robert L., Brown, Steven D., Guss, Adam M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209896/
https://ncbi.nlm.nih.gov/pubmed/28053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-016-0684-x
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