Improved growth rate in Clostridium thermocellum hydrogenase mutant via perturbed sulfur metabolism

BACKGROUND: Metabolic engineering is a commonly used approach to develop organisms for an industrial function, but engineering aimed at improving one phenotype can negatively impact other phenotypes. This lack of robustness can prove problematic. Cellulolytic bacterium Clostridium thermocellum is ab...

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Detalles Bibliográficos
Publicado en:Biotechnol Biofuels
Main Authors: Biswas, Ranjita, Wilson, Charlotte M., Giannone, Richard J., Klingeman, Dawn M., Rydzak, Thomas, Shah, Manesh B., Hettich, Robert L., Brown, Steven D., Guss, Adam M.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209896/
https://ncbi.nlm.nih.gov/pubmed/28053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-016-0684-x
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