Development of a genome-editing CRISPR/Cas9 system in thermophilic fungal Myceliophthora species and its application to hyper-cellulase production strain engineering

BACKGROUND: Over the past 3 years, the CRISPR/Cas9 system has revolutionized the field of genome engineering. However, its application has not yet been validated in thermophilic fungi. Myceliophthora thermophila, an important thermophilic biomass-degrading fungus, has attracted industrial interest f...

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Vydáno v:Biotechnol Biofuels
Hlavní autoři: Liu, Qian, Gao, Ranran, Li, Jingen, Lin, Liangcai, Zhao, Junqi, Sun, Wenliang, Tian, Chaoguang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209885/
https://ncbi.nlm.nih.gov/pubmed/28053662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-016-0693-9
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