Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells

While distinct stem cell phenotypes follow global changes in chromatin marks, single-cell chromatin technologies are unable to resolve or predict stem cell fates. We propose the first such use of optical high content nanoscopy of histone epigenetic marks (epi-marks) in stem cells to classify emergen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Joseph J., Bennett, Neal K., Devita, Mitchel S., Chahar, Sanjay, Viswanath, Satish, Lee, Eunjee A., Jung, Giyoung, Shao, Paul P., Childers, Erin P., Liu, Shichong, Kulesa, Anthony, Garcia, Benjamin A., Becker, Matthew L., Hwang, Nathaniel S., Madabhushi, Anant, Verzi, Michael P., Moghe, Prabhas V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209743/
https://ncbi.nlm.nih.gov/pubmed/28051095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39406
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