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Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production

While Th17 cells can protect against colonization by pathogenic organisms, they also have the potential to become pathogenic and promote autoimmune and inflammatory diseases. Mechanisms that control their pathogenic potential remain poorly understood. Here we show that Ndfip1, a co-activator of the...

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Vydáno v:Sci Rep
Hlavní autoři: Kesewa Layman, Awo Akosua, L. Sprout, Stephanie, Phillips, Dylan, Oliver, Paula M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209687/
https://ncbi.nlm.nih.gov/pubmed/28051111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39649
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