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Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production

While Th17 cells can protect against colonization by pathogenic organisms, they also have the potential to become pathogenic and promote autoimmune and inflammatory diseases. Mechanisms that control their pathogenic potential remain poorly understood. Here we show that Ndfip1, a co-activator of the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kesewa Layman, Awo Akosua, L. Sprout, Stephanie, Phillips, Dylan, Oliver, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209687/
https://ncbi.nlm.nih.gov/pubmed/28051111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39649
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