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M1 macrophages promote aortic valve calcification mediated by microRNA-214/TWIST1 pathway in valvular interstitial cells

Objective: The identification of the biological function of M1 macrophages and the mechanism underlying their role in valvular interstitial cell (VIC) calcification may provide therapeutic targets for the prevention of aortic valve calcification (AVC). This study investigated the mechanism by which...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Xiao-Fei, Wang, Yan, Zheng, Dong-Dong, Xu, Hai-Xia, Wang, Teng, Pan, Min, Shi, Jia-Hai, Zhu, Jian-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209529/
https://ncbi.nlm.nih.gov/pubmed/28078049
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