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RNA-Guided Cas9-Induced Mutagenesis in Tobacco Followed by Efficient Genetic Fixation in Doubled Haploid Plants

Customizable endonucleases are providing an effective tool for genome engineering. The resulting primary transgenic individuals (T(0)) are typically heterozygous and/or chimeric with respect to any mutations induced. To generate genetically fixed mutants, they are conventionally allowed to self-poll...

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Detalles Bibliográficos
Publicado en:Front Plant Sci
Main Authors: Schedel, Sindy, Pencs, Stefanie, Hensel, Götz, Müller, Andrea, Rutten, Twan, Kumlehn, Jochen
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209389/
https://ncbi.nlm.nih.gov/pubmed/28101094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2016.01995
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