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Elastase-Induced Parenchymal Disruption and Airway Hyper Responsiveness in Mouse Precision Cut Lung Slices: Toward an Ex vivo COPD Model

Background: COPD is a progressive lung disease characterized by emphysema and enhanced bronchoconstriction. Current treatments focused on bronchodilation can delay disease progression to some extent, but recovery or normalization of loss of lung function is impossible. Therefore, novel therapeutic t...

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Bibliografiset tiedot
Julkaisussa:Front Physiol
Päätekijät: Van Dijk, Eline M., Culha, Sule, Menzen, Mark H., Bidan, Cécile M., Gosens, Reinoud
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209351/
https://ncbi.nlm.nih.gov/pubmed/28101062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00657
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