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Optimization of Caged Electrophiles for Improved Monitoring of Cysteine Reactivity in Living Cells

Cysteine residues serve critical roles in protein function and are susceptible to numerous posttranslational modifications (PTMs) that serve to modulate the activity and localization of diverse proteins. Many of these PTMs are highly transient and labile, necessitating methods to study these modific...

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Bibliografische gegevens
Gepubliceerd in:Chembiochem
Hoofdauteurs: Abo, Masahiro, Bak, Daniel W., Weerapana, Eranthie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209257/
https://ncbi.nlm.nih.gov/pubmed/27813293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600524
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