Design of Hydrated Porphyrin-phospholipid Bilayers with Enhanced Magnetic Resonance Contrast

Porphyrin-phospholipid can chelate Mn ions in the hydrophobic portion of bilayers, giving rise to magnetic resonance (MR) contrast. However, limited water content within the bilayer diminishes longitudinal MR contrast. We used molecular dynamics (MD) simulations to show that an amine modified porphy...

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Publicado en:Small
Main Authors: Shao, Shuai, Do, Trang Nhu, Razi, Aida, Chitgupi, Upendra, Geng, Jumin, Alsop, Richard J., Dzikovski, Boris G., Rheinstädter, Maikel C, Ortega, Joaquin, Karttunen, Mikko, Spernyak, Joseph A., Lovell, Jonathan F.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209247/
https://ncbi.nlm.nih.gov/pubmed/27739249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201602505
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