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Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression

BACKGROUND: Research on olfactory G-protein coupled receptors (GPCRs) has been severely impeded by poor functional expression in heterologous systems. Previously, we demonstrated that inefficient olfactory receptor (OR) expression at the plasma membrane is attributable, in part, to degradation of en...

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Bibliografiske detaljer
Main Authors: Lu, Min, Staszewski, Lena, Echeverri, Fernando, Xu, Hong, Moyer, Bryan D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC520810/
https://ncbi.nlm.nih.gov/pubmed/15369603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-34
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