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Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression

BACKGROUND: Research on olfactory G-protein coupled receptors (GPCRs) has been severely impeded by poor functional expression in heterologous systems. Previously, we demonstrated that inefficient olfactory receptor (OR) expression at the plasma membrane is attributable, in part, to degradation of en...

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Detalhes bibliográficos
Main Authors: Lu, Min, Staszewski, Lena, Echeverri, Fernando, Xu, Hong, Moyer, Bryan D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC520810/
https://ncbi.nlm.nih.gov/pubmed/15369603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-34
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