Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

Populations are often divided categorically into distinct racial/ethnic groups based on social rather than biological constructs. Genetic ancestry has been suggested as an alternative to this categorization. Herein, we typed over 450,000 CpG sites in whole blood of 573 individuals of diverse Hispani...

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Wydane w:eLife
Główni autorzy: Galanter, Joshua M, Gignoux, Christopher R, Oh, Sam S, Torgerson, Dara, Pino-Yanes, Maria, Thakur, Neeta, Eng, Celeste, Hu, Donglei, Huntsman, Scott, Farber, Harold J, Avila, Pedro C, Brigino-Buenaventura, Emerita, LeNoir, Michael A, Meade, Kelly, Serebrisky, Denise, Rodríguez-Cintrón, William, Kumar, Rajesh, Rodríguez-Santana, Jose R, Seibold, Max A, Borrell, Luisa N, Burchard, Esteban G, Zaitlen, Noah
Format: Artigo
Język:Inglês
Wydane: eLife Sciences Publications, Ltd 2017
Hasła przedmiotowe:
Genes and Chromosomes
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207770/
https://ncbi.nlm.nih.gov/pubmed/28044981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20532
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