Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

Populations are often divided categorically into distinct racial/ethnic groups based on social rather than biological constructs. Genetic ancestry has been suggested as an alternative to this categorization. Herein, we typed over 450,000 CpG sites in whole blood of 573 individuals of diverse Hispani...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Galanter, Joshua M, Gignoux, Christopher R, Oh, Sam S, Torgerson, Dara, Pino-Yanes, Maria, Thakur, Neeta, Eng, Celeste, Hu, Donglei, Huntsman, Scott, Farber, Harold J, Avila, Pedro C, Brigino-Buenaventura, Emerita, LeNoir, Michael A, Meade, Kelly, Serebrisky, Denise, Rodríguez-Cintrón, William, Kumar, Rajesh, Rodríguez-Santana, Jose R, Seibold, Max A, Borrell, Luisa N, Burchard, Esteban G, Zaitlen, Noah
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Genes and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207770/
https://ncbi.nlm.nih.gov/pubmed/28044981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20532
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