Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

Populations are often divided categorically into distinct racial/ethnic groups based on social rather than biological constructs. Genetic ancestry has been suggested as an alternative to this categorization. Herein, we typed over 450,000 CpG sites in whole blood of 573 individuals of diverse Hispani...

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Publicado en:eLife
Autores principales: Galanter, Joshua M, Gignoux, Christopher R, Oh, Sam S, Torgerson, Dara, Pino-Yanes, Maria, Thakur, Neeta, Eng, Celeste, Hu, Donglei, Huntsman, Scott, Farber, Harold J, Avila, Pedro C, Brigino-Buenaventura, Emerita, LeNoir, Michael A, Meade, Kelly, Serebrisky, Denise, Rodríguez-Cintrón, William, Kumar, Rajesh, Rodríguez-Santana, Jose R, Seibold, Max A, Borrell, Luisa N, Burchard, Esteban G, Zaitlen, Noah
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Genes and Chromosomes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207770/
https://ncbi.nlm.nih.gov/pubmed/28044981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20532
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