Validation of Immune Cell Modules in Multicellular Transcriptomic Data

Numerous gene signatures, or modules have been described to evaluate the immune cell composition in transcriptomes of multicellular tissue samples. However, significant diversity in module gene content for specific cell types is associated with heterogeneity in their performance. In order to rank mo...

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Pubblicato in:PLoS One
Autori principali: Pollara, Gabriele, Murray, Matthew J., Heather, James M., Byng-Maddick, Rachel, Guppy, Naomi, Ellis, Matthew, Turner, Carolin T., Chain, Benjamin M., Noursadeghi, Mahdad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207692/
https://ncbi.nlm.nih.gov/pubmed/28045996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169271
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