Persistent T Cell Repertoire Perturbation and T Cell Activation in HIV After Long Term Treatment

OBJECTIVE: In people living with HIV (PLHIV), we sought to test the hypothesis that long term anti-retroviral therapy restores the normal T cell repertoire, and investigate the functional relationship of residual repertoire abnormalities to persistent immune system dysregulation. METHODS: We conduct...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Turner, Carolin T., Brown, James, Shaw, Emily, Uddin, Imran, Tsaliki, Evdokia, Roe, Jennifer K., Pollara, Gabriele, Sun, Yuxin, Heather, James M., Lipman, Marc, Chain, Benny, Noursadeghi, Mahdad
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959740/
https://ncbi.nlm.nih.gov/pubmed/33732256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.634489
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