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Iron Supplementation Reverses the Reduction of Hydroxymethylcytosine in Hepatic DNA Associated With Chronic Alcohol Consumption in Rats

BACKGROUND: Alcohol is known to affect two epigenetic phenomena, DNA methylation and DNA hydroxymethylation, and iron is a cofactor of ten-eleven translocation (TET) enzymes that catalyze the conversion from methylcytosine to hydroxymethylcytosine. In the present study we aimed to determine the effe...

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Dettagli Bibliografici
Pubblicato in:J Cancer Prev
Autori principali: Tammen, Stephanie A., Park, Jung Eun, Shin, Phil Kyung, Friso, Simonetta, Chung, Jayong, Choi, Sang-Woon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society of Cancer Prevention 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207611/
https://ncbi.nlm.nih.gov/pubmed/28053961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15430/JCP.2016.21.4.264
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