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Elucidating the DDK‐dependent step in replication initiation

By phosphorylating specific replication factors, cell cycle kinases ensure that eukaryotic DNA replication is initiated once and only once per mitotic cell division. New work in The EMBO Journal now reveals how DDK‐mediated phosphorylation of Mcm2‐7 helicase subunits is read out by Sld3, which provi...

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Detalles Bibliográficos
Publicado en:EMBO J
Autor Principal: Araki, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207320/
https://ncbi.nlm.nih.gov/pubmed/27006277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694227
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