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Elucidating the DDK‐dependent step in replication initiation
By phosphorylating specific replication factors, cell cycle kinases ensure that eukaryotic DNA replication is initiated once and only once per mitotic cell division. New work in The EMBO Journal now reveals how DDK‐mediated phosphorylation of Mcm2‐7 helicase subunits is read out by Sld3, which provi...
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Yayımlandı: | EMBO J |
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Yazar: | |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2016
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207320/ https://ncbi.nlm.nih.gov/pubmed/27006277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694227 |
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