Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease

Current research on Parkinson’s disease (PD) pathogenesis requires relevant animal models that mimic the gradual and progressive development of neuronal dysfunction and degeneration that characterizes the disease. Polymorphisms in engrailed 1 (En1), a homeobox transcription factor that is crucial fo...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Nordströma, Ulrika, Beauvais, Geneviève, Ghosh, Anamitra, Pulikkaparambil Sasidharan, Baby Chakrapani, Lundblad, Martin, Fuchs, Julia, Joshi, Rajiv L., Lipton, Jack W., Roholt, Andrew, Medicetty, Satish, Feinstein, Timothy N., Steiner, Jennifer A., Escobar Galvis, Martha L., Prochiantz, Alain, Brundin, Patrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207312/
https://ncbi.nlm.nih.gov/pubmed/25281317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.09.012
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