Altering the Proteoglycan State of Transforming Growth Factor β Type III Receptor (TβRIII)/Betaglycan Modulates Canonical Wnt/β-Catenin Signaling

Hyperactive Wnt/β-catenin signaling is linked to cancer progression and developmental abnormalities, making identification of mechanisms controlling Wnt/β-catenin signaling vital. Transforming growth factor β type III receptor (TβRIII/betaglycan) is a transmembrane proteoglycan co-receptor that exis...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jenkins, Laura M., Singh, Priyanka, Varadaraj, Archana, Lee, Nam Y., Shah, Shreya, Flores, Haley V., O'Connell, Kathleen, Mythreye, Karthikeyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207267/
https://ncbi.nlm.nih.gov/pubmed/27784788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748624
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