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The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans

Glycosylation of flagellins is a well recognized property of many bacterial species. In this study, we describe the structural characterization of novel flagellar glycans from a number of hypervirulent strains of C. difficile. We used mass spectrometry (nano-LC-MS and MS/MS analysis) to identify a n...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Bouché, Laura, Panico, Maria, Hitchen, Paul, Binet, Daniel, Sastre, Federico, Faulds-Pain, Alexandra, Valiente, Esmeralda, Vinogradov, Evgeny, Aubry, Annie, Fulton, Kelly, Twine, Susan, Logan, Susan M., Wren, Brendan W., Dell, Anne, Morris, Howard R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207245/
https://ncbi.nlm.nih.gov/pubmed/27758867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749481
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