Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation

Clostridium difficile is the principal cause of nosocomial infectious diarrhea worldwide. The pathogen modifies its flagellin with either a type A or type B O-linked glycosylation system, which has a contributory role in pathogenesis. We study the functional role of glycosyltransferases modifying ty...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Valiente, Esmeralda, Bouché, Laura, Hitchen, Paul, Faulds-Pain, Alexandra, Songane, Mario, Dawson, Lisa F., Donahue, Elizabeth, Stabler, Richard A., Panico, Maria, Morris, Howard R., Bajaj-Elliott, Mona, Logan, Susan M., Dell, Anne, Wren, Brendan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207246/
https://ncbi.nlm.nih.gov/pubmed/27703012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749523
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