Extrinsic Functions of Lectin Domains in O-N-Acetylgalactosamine Glycan Biosynthesis

Glycan biosynthesis occurs mainly in Golgi. Molecular organization and functional regulation of this process are not well understood. We evaluated the extrinsic effect of lectin domains (β-trefoil fold) of polypeptide GalNAc-transferases (ppGalNAc-Ts) on catalytic activity of glycosyltransferases du...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Lorenz, Virginia, Ditamo, Yanina, Cejas, Romina B., Carrizo, Maria E., Bennett, Eric P., Clausen, Henrik, Nores, Gustavo A., Irazoqui, Fernando J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207237/
https://ncbi.nlm.nih.gov/pubmed/27738109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740795
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