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Biosynthesis of O-N-acetylgalactosamine glycans in the human cell nucleus

Biological functions of nuclear proteins are regulated by post-translational modifications (PTMs) that modulate gene expression and cellular physiology. However, the role of O-linked glycosylation (O-GalNAc) as a PTM of nuclear proteins in the human cell has not been previously reported. Here, we ex...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cejas, Romina B., Lorenz, Virginia, Garay, Yohana C., Irazoqui, Fernando J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398145/
https://ncbi.nlm.nih.gov/pubmed/30591584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005524
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