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Stress Granule Induction after Brain Ischemia Is Independent of Eukaryotic Translation Initiation Factor (eIF) 2α Phosphorylation and Is Correlated with a Decrease in eIF4B and eIF4E Proteins

Stress granules (SGs) are cytoplasmic ribonucleoprotein aggregates that are directly connected with the translation initiation arrest response to cellular stresses. Translation inhibition (TI) is observed in transient brain ischemia, a condition that induces persistent TI even after reperfusion, i.e...

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Pubblicato in:J Biol Chem
Autori principali: Ayuso, María I., Martínez-Alonso, Emma, Regidor, Ignacio, Alcázar, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207152/
https://ncbi.nlm.nih.gov/pubmed/27836976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738989
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