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Pharmacokinetics, Immunogenicity, and Safety of Weekly Dosing of Brentuximab in Pediatric Patients with Hodgkin Lymphoma

PURPOSE: Because of the observed success of phase I/II trials, the novel anti-CD30 agent brentuximab vedotin is now being evaluated as a frontline agent in the high-risk pediatric Hodgkin lymphoma trial HLHR13. The objectives of this study were to evaluate the pharmacokinetic variability during week...

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Pubblicato in:Cancer Chemother Pharmacol
Autori principali: Flerlage, Jamie, Metzger, Monika, Wu, Jianrong, Panetta, John C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206991/
https://ncbi.nlm.nih.gov/pubmed/27837256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3180-x
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