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Targeted epigenetic repression of a lymphoma oncogene by sequence-specific histone modifiers induces apoptosis in DLBCL

Alterations to the epigenetic landscape of Diffuse Large B Cell Lymphoma (DLBCL) play a fundamental role in deregulating genes involved in normal lymphocyte differentiation. To determine whether targeted epigenetic therapy could reverse these pathogenic chromatin changes and suppress the expression...

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Pubblicato in:Leuk Lymphoma
Autori principali: Luo, Hong, Schmidt, Jennifer A., Lee, Yi-Shan, Oltz, Eugene M., Payton, Jacqueline E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206989/
https://ncbi.nlm.nih.gov/pubmed/27268204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2016.1190973
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