An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

The Asian lineage of Zika virus (ZIKV) has recently caused epidemics and severe disease. Unraveling the mechanisms causing increased viral transmissibility and disease severity requires experimental systems. We report an infectious cDNA clone of ZIKV that was generated using a clinical isolate of th...

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Publié dans:Cell Host Microbe
Auteurs principaux: Shan, Chao, Xie, Xuping, Muruato, Antonio E., Rossi, Shannan L., Roundy, Christopher M., Azar, Sasha R., Yang, Yujiao, Tesh, Robert B., Bourne, Nigel, Barrett, Alan D., Vasilakis, Nikos, Weaver, Scott C., Shi, Pei-Yong
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206987/
https://ncbi.nlm.nih.gov/pubmed/27198478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.05.004
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