An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

The Asian lineage of Zika virus (ZIKV) has recently caused epidemics and severe disease. Unraveling the mechanisms causing increased viral transmissibility and disease severity requires experimental systems. We report an infectious cDNA clone of ZIKV that was generated using a clinical isolate of th...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Shan, Chao, Xie, Xuping, Muruato, Antonio E., Rossi, Shannan L., Roundy, Christopher M., Azar, Sasha R., Yang, Yujiao, Tesh, Robert B., Bourne, Nigel, Barrett, Alan D., Vasilakis, Nikos, Weaver, Scott C., Shi, Pei-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206987/
https://ncbi.nlm.nih.gov/pubmed/27198478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.05.004
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