Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2(high) Breast Cancer

Aims: Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we investigated whether disruption of the electron transport chain (ETC) is a viable strategy to eliminate Her2(high) disease. Results: We demonstrate th...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Rohlenova, Katerina, Sachaphibulkij, Karishma, Stursa, Jan, Bezawork-Geleta, Ayenachew, Blecha, Jan, Endaya, Berwini, Werner, Lukas, Cerny, Jiri, Zobalova, Renata, Goodwin, Jacob, Spacek, Tomas, Alizadeh Pesdar, Elham, Yan, Bing, Nguyen, Maria Nga, Vondrusova, Magdalena, Sobol, Margaryta, Jezek, Petr, Hozak, Pavel, Truksa, Jaroslav, Rohlena, Jakub, Dong, Lan-Feng, Neuzil, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206771/
https://ncbi.nlm.nih.gov/pubmed/27392540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6677
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