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Expression of KIR2DS1 by decidual natural killer cells increases their ability to control placental HCMV infection

The combination of the activating killer cell Ig-like receptor 2DS1 (KIR2DS1) expressed by maternal decidual natural killer cells (dNK) and the presence of its ligand, the HLA-C allotype HLA-C2, expressed by fetal trophoblasts, reduces the risk of developing pregnancy complications. However, no mole...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Crespo, Ângela C., Strominger, Jack L., Tilburgs, Tamara
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206558/
https://ncbi.nlm.nih.gov/pubmed/27956621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617927114
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