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Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s
Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung. In Th2 cells, T cell receptor (TCR) signaling activates the transcription factors nuclear factor of activated T cell...
Gespeichert in:
| Veröffentlicht in: | J Exp Med |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206504/ https://ncbi.nlm.nih.gov/pubmed/28011865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161274 |
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