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The cysteinyl leukotriene 3 receptor regulates expansion of IL-25–producing airway brush cells leading to type 2 inflammation

Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct EpC programs are regulated remains poorly understood. Here, we report that inhalation of aeroallergens leads to expansion of airway brush cells (BrCs), specializ...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Bankova, Lora G., Dwyer, Daniel F., Yoshimoto, Eri, Ualiyeva, Saltanat, McGinty, John W., Raff, Hannah, von Moltke, Jakob, Kanaoka, Yoshihide, Austen, K. Frank, Barrett, Nora A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599626/
https://ncbi.nlm.nih.gov/pubmed/30291131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aat9453
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