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Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma–induced retinal pathology
Children with neurofibromatosis type 1 (NF1) develop low-grade brain tumors throughout the optic pathway. Nearly 50% of children with optic pathway gliomas (OPGs) experience visual impairment, and few regain their vision after chemotherapy. Recent studies have revealed that girls with optic nerve gl...
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| Published in: | J Exp Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206494/ https://ncbi.nlm.nih.gov/pubmed/27923908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160447 |
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