Hyaluromycin, a Novel Hyaluronidase Inhibitor, Attenuates Pancreatic Cancer Cell Migration and Proliferation

Pancreatic ductal adenocarcinoma (PDAC) is characterized by accelerated production and degradation of hyaluronan (HA), a major component of extracellular matrix involved in the malignant phenotype of cancer. In particular, increased hyaluronidase (HYAL) activity plays a critical role in cancer progr...

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Vydáno v:J Oncol
Hlavní autoři: Kohi, Shiro, Sato, Norihiro, Koga, Atsuhiro, Hirata, Keiji, Harunari, Enjuro, Igarashi, Yasuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206452/
https://ncbi.nlm.nih.gov/pubmed/28096814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9063087
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