Hyaluromycin, a Novel Hyaluronidase Inhibitor, Attenuates Pancreatic Cancer Cell Migration and Proliferation

Pancreatic ductal adenocarcinoma (PDAC) is characterized by accelerated production and degradation of hyaluronan (HA), a major component of extracellular matrix involved in the malignant phenotype of cancer. In particular, increased hyaluronidase (HYAL) activity plays a critical role in cancer progr...

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Bibliographische Detailangaben
Veröffentlicht in:J Oncol
Hauptverfasser: Kohi, Shiro, Sato, Norihiro, Koga, Atsuhiro, Hirata, Keiji, Harunari, Enjuro, Igarashi, Yasuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206452/
https://ncbi.nlm.nih.gov/pubmed/28096814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9063087
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