Platelets are responsible for the accumulation of β-amyloid in blood clots inside and around blood vessels in mouse brain after thrombosis

INTRODUCTION: Platelets contain beta-amyloid precursor protein (APP) as well as Aβ peptide (Aβ) that can be released upon activation. During thrombosis, platelets are concentrated in clots and activated. METHODS: We used in vivo fluorescent analysis and electron microscopy in mice to determine to wh...

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Pubblicato in:Brain Res Bull
Autori principali: Kucheryavykh, Lilia Y., Dávila-Rodríguez, Josué, Rivera-Aponte, David E., Zueva, Lidia V., Washington, A. Valance, Sanabria, Priscilla, Inyushin, Mikhail Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5205543/
https://ncbi.nlm.nih.gov/pubmed/27908798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2016.11.008
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