Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile

DNA replication is an essential and conserved process in all domains of life and may serve as a target for the development of new antimicrobials. However, such developments are hindered by subtle mechanistic differences and limited understanding of DNA replication in pathogenic microorganisms. Clost...

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Bibliografiset tiedot
Julkaisussa:Open Biol
Päätekijät: van Eijk, Erika, Paschalis, Vasileios, Green, Matthew, Friggen, Annemieke H., Larson, Marilynn A., Spriggs, Keith, Briggs, Geoffrey S., Soultanas, Panos, Smits, Wiep Klaas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Royal Society 2016
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204125/
https://ncbi.nlm.nih.gov/pubmed/28003473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160272
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