Human splicing diversity and the extent of unannotated splice junctions across human RNA-seq samples on the Sequence Read Archive

BACKGROUND: Gene annotations, such as those in GENCODE, are derived primarily from alignments of spliced cDNA sequences and protein sequences. The impact of RNA-seq data on annotation has been confined to major projects like ENCODE and Illumina Body Map 2.0. RESULTS: We aligned 21,504 Illumina-seque...

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Vydáno v:Genome Biol
Hlavní autoři: Nellore, Abhinav, Jaffe, Andrew E., Fortin, Jean-Philippe, Alquicira-Hernández, José, Collado-Torres, Leonardo, Wang, Siruo, Phillips III, Robert A., Karbhari, Nishika, Hansen, Kasper D., Langmead, Ben, Leek, Jeffrey T.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203714/
https://ncbi.nlm.nih.gov/pubmed/28038678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1118-6
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