Purine Biosynthesis Metabolically Constrains Intracellular Survival of Uropathogenic Escherichia coli

The ability to de novo synthesize purines has been associated with the intracellular survival of multiple bacterial pathogens. Uropathogenic Escherichia coli (UPEC), the predominant cause of urinary tract infections, undergoes a transient intracellular lifestyle during which bacteria clonally expand...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Shaffer, Carrie L., Zhang, Ellisa W., Dudley, Anne G., Dixon, Beverly R. E. A., Guckes, Kirsten R., Breland, Erin J., Floyd, Kyle A., Casella, Daniel P., Algood, Holly M. Scott, Clayton, Douglass B., Hadjifrangiskou, Maria
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203662/
https://ncbi.nlm.nih.gov/pubmed/27795353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00471-16
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