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Purine Biosynthesis Metabolically Constrains Intracellular Survival of Uropathogenic Escherichia coli

The ability to de novo synthesize purines has been associated with the intracellular survival of multiple bacterial pathogens. Uropathogenic Escherichia coli (UPEC), the predominant cause of urinary tract infections, undergoes a transient intracellular lifestyle during which bacteria clonally expand...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: Shaffer, Carrie L., Zhang, Ellisa W., Dudley, Anne G., Dixon, Beverly R. E. A., Guckes, Kirsten R., Breland, Erin J., Floyd, Kyle A., Casella, Daniel P., Algood, Holly M. Scott, Clayton, Douglass B., Hadjifrangiskou, Maria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203662/
https://ncbi.nlm.nih.gov/pubmed/27795353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00471-16
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