Purine Biosynthesis Metabolically Constrains Intracellular Survival of Uropathogenic Escherichia coli

The ability to de novo synthesize purines has been associated with the intracellular survival of multiple bacterial pathogens. Uropathogenic Escherichia coli (UPEC), the predominant cause of urinary tract infections, undergoes a transient intracellular lifestyle during which bacteria clonally expand...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Shaffer, Carrie L., Zhang, Ellisa W., Dudley, Anne G., Dixon, Beverly R. E. A., Guckes, Kirsten R., Breland, Erin J., Floyd, Kyle A., Casella, Daniel P., Algood, Holly M. Scott, Clayton, Douglass B., Hadjifrangiskou, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203662/
https://ncbi.nlm.nih.gov/pubmed/27795353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00471-16
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