A copper-thiolate polynuclear cluster in the ACE1 transcription factor.

ACE1 is the transcriptional activator of the metallothionein (CUP1 locus) gene in Saccharomyces cerevisiae. Previous data had implicated the N-terminal domain of ACE1 as responsible for the Cu-dependent specific DNA binding. An expression system in Escherichia coli was constructed to enable the isol...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Dameron, C T, Winge, D R, George, G N, Sansone, M, Hu, S, Hamer, D
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52035/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2068093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6127
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