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A copper-thiolate polynuclear cluster in the ACE1 transcription factor.

ACE1 is the transcriptional activator of the metallothionein (CUP1 locus) gene in Saccharomyces cerevisiae. Previous data had implicated the N-terminal domain of ACE1 as responsible for the Cu-dependent specific DNA binding. An expression system in Escherichia coli was constructed to enable the isol...

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Detalhes bibliográficos
Main Authors: Dameron, C T, Winge, D R, George, G N, Sansone, M, Hu, S, Hamer, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52035/
https://ncbi.nlm.nih.gov/pubmed/2068093
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