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Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein
Several arenaviruses, chiefly Lassa (LASV) in West Africa, cause hemorrhagic fever (HF) disease in humans and pose important public health problems in their endemic regions. To date, there are no FDA-approved arenavirus vaccines and current anti-arenaviral therapy is limited to the use of ribavirin...
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| Udgivet i: | Virology |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201438/ https://ncbi.nlm.nih.gov/pubmed/27855284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.11.001 |
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