Brown Algae Polyphenol, a Prolyl Isomerase Pin1 Inhibitor, Prevents Obesity by Inhibiting the Differentiation of Stem Cells into Adipocytes

BACKGROUND: While screening for an inhibitor of the peptidyl prolyl cis/trans isomerase, Pin1, we came across a brown algae polyphenol that blocks the differentiation of fibroblasts into adipocytes. However, its effectiveness on the accumulation of fat in the body has never been studied. METHODOLOGY...

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Udgivet i:PLoS One
Main Authors: Suzuki, Atsuko, Saeki, Toshiyuki, Ikuji, Hiroko, Uchida, Chiyoko, Uchida, Takafumi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201290/
https://ncbi.nlm.nih.gov/pubmed/28036348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168830
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