Src Inhibition Can Synergize with Gemcitabine and Reverse Resistance in Triple Negative Breast Cancer Cells via the AKT/c-Jun Pathway

PURPOSE: Gemcitabine-based chemotherapy remains one of the standards in management of metastatic breast cancer. However, intrinsic and acquired resistance to gemcitabine inevitably occurs. The aims of this study were to assess the efficacy of the combination of src inhibition and gemcitabine in gemc...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wu, Zhen-Hua, Lin, Chen, Liu, Ming-Ming, Zhang, Jian, Tao, Zhong-Hua, Hu, Xi-Chun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201240/
https://ncbi.nlm.nih.gov/pubmed/28036386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169230
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