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Src Inhibition Can Synergize with Gemcitabine and Reverse Resistance in Triple Negative Breast Cancer Cells via the AKT/c-Jun Pathway

PURPOSE: Gemcitabine-based chemotherapy remains one of the standards in management of metastatic breast cancer. However, intrinsic and acquired resistance to gemcitabine inevitably occurs. The aims of this study were to assess the efficacy of the combination of src inhibition and gemcitabine in gemc...

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מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Wu, Zhen-Hua, Lin, Chen, Liu, Ming-Ming, Zhang, Jian, Tao, Zhong-Hua, Hu, Xi-Chun
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201240/
https://ncbi.nlm.nih.gov/pubmed/28036386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169230
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