Targeting BTK through microRNA in chronic lymphocytic leukemia

Bruton’s tyrosine kinase (BTK) is a critical mediator of survival in B-cell neoplasms. Although BTK inhibitors have transformed therapy in chronic lymphocytic leukemia (CLL), patients with high-risk genetics are at risk for relapse and have a poor prognosis. Identification of novel therapeutic strat...

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Vydáno v:Blood
Hlavní autoři: Bottoni, Arianna, Rizzotto, Lara, Lai, Tzung-Huei, Liu, Chaomei, Smith, Lisa L., Mantel, Rose, Reiff, Sean, El-Gamal, Dalia, Larkin, Karilyn, Johnson, Amy J., Lapalombella, Rosa, Lehman, Amy, Plunkett, William, Byrd, John C., Blachly, James S., Woyach, Jennifer A., Sampath, Deepa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201097/
https://ncbi.nlm.nih.gov/pubmed/27756747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-07-727750
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