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Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development
Secreted Dickkopf (Dkk) proteins are major Wnt pathway modulators during organ development. Dkk1 has been widely studied and acts as a general Wnt inhibitor. However, the molecular function of other Dkks remains largely unknown. Here, we show that Dkk4 selectively inhibits a subset of Wnts, but is f...
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Publicado no: | Development |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201035/ https://ncbi.nlm.nih.gov/pubmed/27864382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143909 |
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